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The Leica CM3050 S cryostat was designed primarily for the demanding needs of cryosectioning systems in the field of biomedical, neuro-anatomical and pharmaceutical research. Particularly when working with delicate specimens for example brain samples in neuroscience the precise specimen orientation and the specimen feed system via step motor guarantees reproducible thin serial sections of maximum quality. The Leica motorized CM3050 S is available with or without active specimen cooling. An ergonomic height adjustment can be retrofitted, enabling the user to operate the cryostat in a sitting or standing position