Description
Leica VT1000 S is the premier industry standard for high-quality sectioning of fixed or unfixed fresh tissue under physiological conditions. Designed to bypass time-consuming freezing or aggressive chemical embedding steps, this versatile vibrating microtome flawlessly preserves vital cell morphology, enzyme activity, and cell viability across delicate specimens.
Key Technical Specifications
The Leica VT1000 S platform offers precise mechanical controls to cleanly cut variable non-homogeneous specimens without tearing or introducing surface ripples:
- Sectioning Frequency: 0 to 100 Hz (adjustable via dial)
- Vibration Amplitude: Selectable at 0.2, 0.4, 0.6, 0.8, and 1.0 mm
- Blade Travel Speed: Fine electronic adjustments from 0.025 to 2.5 mm/s
- Total Vertical Specimen Stroke: 15 mm (motorized standard feed)
- Maximum Specimen Size: 70 x 40 x 15 mm
- Sectioning Window: Freely programmable electronic adjustment
- Instrument Dimensions: 480 mm × 360 mm × 200 mm (W x D x H)
- Power Supply: Universal compatibility (100–240 V, 50/60 Hz)
Core Performance Features
⏱️ Fully Automated & Single Cut Modes
Accelerate your sectioning throughput with an automated, continuous stroke option. When paired with the high-speed blade return stroke and customized sectioning window, the mechanism cuts down overall processing times even for micro-specimens.
🛡️ Integrated Sample Protection
An adjustable specimen retraction feature safely pulls the tissue clear during the blade’s return path. This eliminates drag friction, minimizing friction defects and ensuring surface cellular viability.
🔬 Ergonomic Handling & Visualization
Features built-in hand rests to facilitate comfortable prolonged manual harvesting. Every baseline configuration includes a 2x magnifier attachment to seamlessly evaluate slice quality over a high-contrast dark buffer tray.
Elite Research Applications
Because it excels at cutting un-embedded tissues without destroying biological matrices, the VT1000 S is highly utilized in fields like:
- Neuroscience & Neurophysiology: Perfect for brain slicing, spinal mapping, and live-cell immunohistochemistry preparation.
- Electrophysiology: Reliably isolates thick, highly uniform slices critical for path-clamp recording consistency.
- Botany Research: Cleanly cuts through cellular structures, fibrous root matrices, and soft plant tissues.
- Industrial Materials: Offers distortion-free sectioning of synthetic polymer foams, hydrogels, and complex multi-layered porous films.









