Description
The Leica RM2235 is a market-leading manual rotary microtome engineered for high-throughput routine histology, clinical diagnostics, and demanding research applications. Recognized as a modern industry standard, the RM2235 builds on the legendary precision of its predecessors while introducing advanced ergonomic features, enhanced user safety, and a ultra-stable design that delivers flawless, chatter-free sections down to 1 micron.
Whether sectioning standard paraffin blocks or harder biomedical specimens, the Leica RM2235 provides unparalleled reproducibility, mechanical longevity, and operational comfort for high-volume lab environments.
Key Features & Benefits
- Advanced Cross-Roller Bearing Feed System: Features a highly precise, zero-backlash mechanical feed system utilizing advanced cross-roller bearings. This ensures completely uniform stroke movement and maximum stability, eliminating micro-chatter even when cutting dense or hard specimens.Â
- Patented Force Compensation & Smooth Handwheel: Equipped with Leica’s patented mass-balanced force compensation system. This pre-stressed spring mechanism counterbalances the centrifugal forces of the vertical stroke, resulting in an effortless, ultra-smooth handwheel rotation that significantly reduces user fatigue and repetitive strain injuries (RSI).
- Next-Generation Ergonomic Design: Designed alongside laboratory professionals, featuring a patented, height-adjustable user hand rest that reduces tension in the shoulders and neck. A spacious, integrated storage tray sits on top of the instrument housing to keep forceps, brushes, and spare blades within arm’s reach.
- Premium Lab Safety Systems: Built with an uncompromising dual-safety locking mechanism. The handwheel can be securely locked in any position using a quick-locking lever, and the standard 12 o’clock locking brake automatically secures the specimen head in its upper limit for safe block changing.Â
- Adjustable Trimming System: A highly accessible lateral trimming lever lets users toggle quickly between predefined trimming steps (10 µm and 30 µm) for fast specimen facing before precision sectioning.Â
- Seamless, Chemical-Resistant Housing: The exterior features a totally enclosed, one-piece protective housing constructed from impact-resistant and chemical-resistant plastics. The seamless design is incredibly easy to wipe down and prevents paraffin debris from migrating into the internal micrometer mechanics.
Technical Specifications
- Section Thickness Range: 1 µm to 60 µm
- Increments: 1 µm to 10 µm (in 1 µm steps); 10 µm to 20 µm (in 2 µm steps); 20 µm to 60 µm (in 5 µm steps)
- Horizontal Specimen Feed: 30 mm
- Vertical Specimen Stroke: 70 mm
- Specimen Orientation: 8° (x, y, z axes) with precise zero-point positioning
- Specimen Retraction: Standard 20 µm (can be deactivated)
- Section Thickness Range: 1 µm to 60 µm
Applications
The Leica RM2235 seamlessly supports critical clinical diagnostic pathways and research protocols, producing immaculate ribboning and high-fidelity sections for:Â
- Routine Hematoxylin and Eosin (H&E) staining
- High-precision Immunohistochemistry (IHC) and Immunofluorescence (IF)
- Complex Molecular Pathology & In-situ Hybridization (ISH)
